Hepatitis B Virus Core-Related Antigens as Markers for Monitoring Chronic Hepatitis B Infection

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Hepatitis B virus core-related antigens as markers for monitoring chronic hepatitis B infection.

A sensitive chemiluminescence enzyme immunoassay has been developed for hepatitis B virus (HBV) core-related antigen (HBcrAg) detection. We aimed to investigate the usefulness of HBcrAg measurement for monitoring chronic hepatitis B disease. HBcrAg levels were measured by a chemiluminescence enzyme immunoassay in 54 untreated patients and 39 patients treated with either entecavir or lamivudine....

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Hepatitis B Virus Core-related Antigens as a Marker for Monitoring of Chronic Hepatitis B Infection

*Correspondence and reprint request: Dr. Man-Fung Yuen, Department of Medicine, The University of Hong Kong Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China. Tel: (852) 28553984 Fax: (852) 28725828 E-mail: [email protected] AC CE PT ED Copyright © 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Clin. Microbiol. doi:10.1128/JCM.00...

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  Background and Objective: Presence of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is defined, as isolated anti-HBc. little is known about the clinical significance of the isolated anti-HBc in hepatitis B virus (HBV) infections. The aim of this study was to assess the significance of anti-HBc as the onl...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2007

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.00366-07